What are White Matter Hyperintensities Made of?

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What are White Matter Hyperintensities Made of?

1. On page 3, the right column, first full paragraph, the third sentence read, “A large multicenter study of WMH in 2699 stroke patients in 11 stroke centers in China suggested....” It has been changed to read, “A large multicenter study of WMH in 2699 stroke patients in 11 stroke centers in Korea suggested....” 2. On page 5, the left column, the third complete sentence read, “A recent very lar...

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What are White Matter Hyperintensities Made of?

W hite matter hyperintensities (WMH) of presumed vascular origin, also referred to as leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or computed tomography (CT) in older subjects and in patients with stroke and dementia. They are associated with cognitive impairment, triple the risk of stroke and double the risk of dementia. Knowledge of their pathology deriv...

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What are white matter hyperintensities made of? Relevance to vascular cognitive impairment.

W hite matter hyperintensities (WMH) of presumed vascular origin, also referred to as leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or computed tomography (CT) in older subjects and in patients with stroke and dementia. They are associated with cognitive impairment, triple the risk of stroke and double the risk of dementia. Knowledge of their pathology deriv...

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What do white matter hyperintensities really represent?

See related article, pages 600 – 606. W hite matter hyperintensities and small, incidentally found brain infarcts are common findings on MRI, especially in old people, usually regarded as surrogates of small vessel disease. Debette and colleagues have studied the significance of such changes in upper middle-aged persons using the Framingham Offspring cohort. Volumetric brain MRI and neuropsycho...

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MTI of white matter hyperintensities.

The severity of tissue changes associated with incidental white matter hyperintensities (WMH) in the elderly cannot be sufficiently determined by conventional MRI. We, therefore, performed a regional analysis of the magnetization transfer ratio (MTR) maps obtained on a 1.5 T scanner from 198 neurologically asymptomatic participants of the Austrian Stroke Prevention Study (mean age 70, age range...

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ژورنال

عنوان ژورنال: Journal of the American Heart Association

سال: 2015

ISSN: 2047-9980,2047-9980

DOI: 10.1161/jaha.114.001140